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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Magn Reson Med. 2016 Mar 28;77(4):1419–1428. doi: 10.1002/mrm.26226

Figure 2.

Figure 2

Schema of the two methods used for the acquisition of the [2-13C]DHAc spectra. For the “Multi-frequency shifts” method, the RF offset was changed to center a 21.6ppm effective excitation band for the spatially-selective pulses used on the metabolite region of interest, although slice misregistration resulted in excitation out of this band. The TR between excitations on the same band was 5 s. Conversely, the SPSP RF pulse allowed for acquisition of all the resonances of interest in a single excitation with no slice misregistration, and a TR of 3 s was chosen for dynamic spectra acquisition. Liver and kidney acquisitions were interleaved in both methods.