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. 2016 Sep 16;10:24–33. doi: 10.1016/j.redox.2016.09.001

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© 2016 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3. — Measurement of the expression levels of CYP46A1 and CYP27A1 in AD brain specimens. Gene expression was quantified by real-time RT-PCR in specimens at different stages of AD. Brain specimens of healthy subjects were taken as controls. Data, normalized to β₂-microglobulin, are expressed as mean values±SD. Early AD (Braak stages I, II); late AD (Braak stages IV to VI). Control brain specimens: n=4; early AD specimens: n=5; late AD specimens: n=8. Brain tissues from the frontal and occipital cortex were analyzed separately. ***P<0.001vs controls; ^#P<0.05 and ^###P<0.001 vs early AD.