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. 2016 Sep 15;8(9):3893–3902.

Figure 1.

Figure 1

Synergistic induction of apoptosis by ABT-199 and panobinostat (Pan) in AML cell lines determined by annexin V/PI staining and flow cytometry and CompuSyn software analyses. (A and B) THP-1 (A) and U937 (B) cells were treated with ABT-199 and panobinostat, alone or in combination, for 24 h and then subjected to annexin V/PI staining and flow cytometry analysis. CI values were calculated using CompuSyn software. **indicates P<0.01 and ***indicates P<0.001. (C and D) Whole cell lysates were subjected to Western blotting and probed with the indicated antibodies.