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Subfailure overstretch impaired contractility in the RA model. (A) Photograph of representative overstretch injury in the RA model. (B) Contractile response to 110 mM KCl in RA after subfailure overstretch injury (n = 18). Treatment with the P2X7R antagonist oATP (n = 9) and A438079 (n = 9) restored contractile response. n = 9, *p < 0.05.
