Figure 1.

Weight gain in Stx-treated mice. Three groups of initially 16 mice were injected with either PBS (control), Stx1 (1500 ng), or Stx2a (7 ng), and weighed prior to sacrificing four mice every 24 h for histological studies. The average weight of the remaining mice at each time point is plotted. As observed in previous studies, mice injected with PBS (circles) gained weight over the 72 h period, while injection of Stx2a (triangles) resulted in a statistically significant loss of weight at 24, 48, and 72 h post-injection (^*P < 0.01, ^**P < 0.0032). Compared to the PBS alone injected population, mice injected with Stx1 (squares) gained less weight, although the differences were not statistically significant.