TABLE 1. General information of second generation antipsychotic in the treatment of major depressive disorder^a.

^aTable adapted from article by Han et al.14 ^bLevel of evidence defined based on the CANMAT guideline, Level 1: Meta-analysis or replicated double-blind (DB), randomized controlled trial (RCT) that includes a placebo condition, Level 2: At least one DB- randomized controlled trial (RCT) with placebo or active comparison condition, Level 3: Prospective uncontrolled trial with at least ten or more subjects; Level 4: Anecdotal reports or expert opinion.