Fig. 1.

Schematic of sdAb-QDs prepared previously, through an extended histidine tail on the sdAb and through the current method utilizing biotinylated QDs and sdAb-RZ. The left side shows a DHLA-capped QD onto which sdAb have been conjugated through an extended histidine tail. The right side shows a QD capped with 80% DHLA-PEG550-OMe and 20% DHLA-PEG400-biotin onto which sdAb-RZ are conjugated through the RZ-biotin interaction. The structure of the sdAb is from PDB:4W70 [40] and the RZ structure from PBD:3EW2 [14]. The components are not drawn to scale.