Table 1.

TEAEs in study 326 and in the Asian subanalysis [10,23]

Parameter	Study 326 [10]		Asian subanalysis [23]
Donepezil 23 mg/day (n = 963)	Donepezil 10 mg/day (n = 471)	Donepezil 23 mg/day (n = 145)	Donepezil 10 mg/day (n = 78)
Patients with at least 1 TEAE	73.7	63.7	82.1	71.8
TEAEs
Nausea	11.8	3.4	15.9	6.4
Vomiting	9.2	2.5	15.2	3.8
Diarrhea	8.3	5.3	6.9	3.8
Anorexia	5.3	1.7	10.3	2.6
Dizziness	4.9	3.4	8.3	6.4
Weight decrease	4.7	2.5	5.5	3.8
Headache	4.3	3.2	6.9	3.8
Patients who discontinued due to TEAEs	18.6	7.9	21.4	10.3
Most common TEAEs leading to discontinuation
Vomiting	2.9	0.4	4.1	1.3
Nausea	1.9	0.4	2.1	0

Values are percentages.