Table 1.

Most frequent conditions for MSCs therapies clinical trials

Source of MSCs	Condition	Total number of clinical trials	Autologous	Allogeneic
BM-MSCs	Ischemia*	28	21	8
	Bone regeneration	18, thereof 9 TE#	14	3
	Graft rejection	12	4	9
	Degenerative diseases§	12	9	2
	Lung diseases†	9	3	6
	Multiple sclerosis	9	9	0
	Amyotrophic lateral sclerosis	3	3	0
AT-MSCs	Ischemia*	10	6	2
	Degenerative diseases§	8	7	1
	Crohn's disease	3	1	2
	Spinal cord injury	2	2	0
	Liver cirrhosis	2	2	0
	Multiple sclerosis	2	2	0
	Amyotrophic lateral sclerosis	2	1	1
BM-MSCs	GvHD	23	1	20
AT-MSCs	GvHD	3	1	2

^*Including myocardial infarction, stroke, and critical limb ischemia.

^#Tissue engineering, e.g. MSCs seeded on bioceramic plates or immobilized in allogeneic bone prior to implantation.

^§e.g. osteoarthritis, degenerative disc disease.

^†e.g. emphysema, respiratory distress syndrome.