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. 2016 Jul 19;4(3):24. doi: 10.3390/vaccines4030024

Figure 1.

Figure 1

STCL-specific immune responses in BALB/c and DBA/1 mice. The mice were given STCL vaccine (0.1 mg per dose per mouse) with either a low dose of PC1 (108 CFU per dose per mouse) or a high dose (1011 CFU per dose per mouse) on days 0 and 14. In addition, the mice received PC1 alone on days −1 and 13. The vaccine group received the STCL vaccine alone. PBS group received PBS as the negative control. On day 28, blood samples were collected, and assayed for IgG subclasses in BALB/c (A) and DBA/1 (B) mice. Cytokine levels in spleens were quantified in the BALB/c (C) and DBA/1 (D) mice. Antibody values are expressed as units mL−1 + SEM. Cytokine results are expressed as the mean + SEM. There were 10 mice in each group. Results from one representative experiment out of two are presented. * p < 0.05 compared to vaccine group; † p < 0.05 compared to PBS group.