Table 1.

Demographics of HCV infected patients enrolled in HCV003 trial.

Regimen	Patient	Arm	Age (years)	Sex	HCV Genotype	Baseline Viral Load (IU/mL)	HLA-A	HLA-B	HLA-C	HLA-DR	HLA-DQ	RVR	EVR	SVR
14wk IFNa/Rib lead-in pre-vaccination	357	A	58	M	1a	33.7 × 106	02/30	13/62	06/10	04/07	02/08	No	No	No
	362	A	43	M	1a	32,000	01/29	08/44	07/16	01/07/53	02/05	Yes	Yes	No
	364	A	46	F	1a	109,382	03/24	7	07/16	01/103	05	Yes	Yes	No
	366	A	36	F	1a	2.0 × 106	02/33	07/65	07/08	11/103	05/07	Yes	Yes	Yes
2 weeks IFNa/Rib lead-in pre-vaccination	350	B	56	M	1a	1.8 × 106	24/26	35/51	04/15	04/09	08/09	Yes	Yes	No
	351	B	38	M	1b	2.7 × 106	02	36/50	06/10	-	-	Yes	Yes	Yes
	352	B	52	M	1b	9.4 × 106	03/24	07	07	01/15/51	05/06	No	Yes	No
	354	B	51	M	1a	3.2 × 106	01/02	08/62	07/09	52/53	02/08	No	No	No
	356	B	38	M	1b	173,764	11/66	35/41	04/17	13	06	Yes	Yes	w/d
Vaccinated treatment-naïve	355	C	59	M	1a	467,000	02/03	27/65	02/08	52/53	06/07	n/a	n/a	n/a
	358	C	49	F	1a	42,000	03/68	44/60	10/16	07/13/52/53	02/06	n/a	n/a	n/a
	359	C	35	M	1a	237,000	01/66	08/41	07/17	52/53	02	n/a	n/a	n/a
	360	C	51	F	1a	21.7 × 106	02/24	35/44	07/09	04/11/52/53	07	n/a	n/a	n/a

M = male. F = female. RVR= rapid virological response (viral load <50 IU/mL at wk 4 of treatment). EVR = early virological response (viral load undetectable at week 12 of treatment). SVR = sustained virological response, “yes” indicates undetectable viral load 6 months after the end of treatment. n/a = not applicable w/d = withdrawn from study.