Table 1. NS8593 inhibits pre-implantation embryo development to the blastocyst stage of mouse WT CD1 zygotes.

Treatment	#2nd PB/2PNa	#2-Cells (%)b	#Blastocysts (%)b
Control	55	41 (75%)	27 (66%)
NS8593-10 μM	59	47 (80%)	1 (0.02%)

^aZygotes were collected 15 h post hCG. Four replicates, PB: Polar Body, PN: Pro-Nucleus.

^b2-cell embryos were evaluated at 24 h and blastocysts at 96 h post collection, respectively.