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. 2016 Sep 29;6:34579. doi: 10.1038/srep34579

Figure 1. Integrative transcriptomic and network analysis.

Figure 1

Microarray datasets from PD and MDD were downloaded from NextBio Research. Differential gene expression and microarray meta-analysis were performed using NextBio. Differentially expressed genes shared between PD and MDD were analyzed using network and pathway analysis in GeneMANIA. The most significant gene ranked in meta-analysis and in network analysis was tested in RT-qPCR assays in RNA samples from blood of early stage and drug naïve PD patients and HC nested in PPMI.