Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Sep 29;6:34579. doi: 10.1038/srep34579

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(a) Meta-analysis results for NAMPT mRNA across the four PD (green) and MDD (blue) datasets used in this study. NAMPT was significantly upregulated in both datasets from untreated PD patients compared to HC. (b) RT-qPCR assays were used to confirm the results from the meta-analysis. Relative abundance of NAMPT mRNA in blood of 99 PD patients (green) compared to 101 HC (white) in samples obtained from PPMI. The geometric mean of two reference genes, GAPDH and PGK1, were used to normalize for input RNA. A Student t-test (two-tailed) was used to assess the significance between PD and controls. Error bars represent 95% confidence interval. A p-value of 0.05 or less was regarded as significant (c) ROC analysis of NAMPT resulted in an AUC value of 0.63.