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. 2016 Sep 29;6:33980. doi: 10.1038/srep33980

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Copyright © 2016, The Author(s)

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Secretion of albumin by hepatocytes cultured on collagen I-coated PDMS substrate (a) and glass slides (b) in 75 μm and 1 mm tall μCs. Hepatocytes grown for 7 days on collagen I-coated glass slides in 12-well plates were used as control (denoted as standard). The data indicate means ± SD (n = 3). *p < 0.05. (c) Immunostaining images of albumin (green) and MRP2 (red) in hepatocytes cultured for 7 days in all-PDMS microchambers with variable heights. Nuclei are stained by DAPI (blue). Scale bar = 50 μm.