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. 2016 Sep 29;6:34529. doi: 10.1038/srep34529

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Once cells are treated with DIM, DIM prevents p54/nrb from binding to PCGEM1 promoter, and decreases the expression of PCGEM1, thus resulting in the down-regulation of AR3. TSS: transcription start site.