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Casp2−/− mice have higher oxidative damage and inflammation. (a) Lipid peroxidation, (b) oxidatively modified DNA; 8-OHdG, (c) SOD (total) activity and (d) protein carbonyls were determined in mice liver lysates. (e) Alanine transaminase (ALT), (f) Alkaline phosphatase (ALP), (g) IL6, (h) IL1α and (i) IL1β were measured in serum. Values are given as mean±S.E.M. (n=6, PBS and n=11, DEN). Statistics were performed using Student's t-test. *P<0.05, **P<0.01 and ***P<0.001
