Plasma levels of cNH concentrations are elevated in 2 Gy irradiated ferrets at two time points prior to the time of death (which occurs in ferrets at ~13 days or 312 h). Neutrophil and lymphocyte counts are significantly reduced at all time points shown. When cNH levels were compared, statistically significant differences among treatment groups (vs. the preirradiation group) were determined by the Wilcoxon Mann-Whitney test; sample sizes for each treatment group are as follows: preirradiation =17, 4 h =14, 12 h =13, 48 h = 15, 168 h = 16 and 312 h = 32 (the assay was performed once). When blood cell counts were compared, statistically significant differences among treatment groups were determined by the Student’s t test. Sample sizes for each group are reported in the table shown below the figure.