Table 2.

Effect of the fractions of Croton macrostachyus leaves on castor oil induced enteropooling in mice

Dose administered	Volume of intestinal content (ml)	% of inhibition	Mean weight of intestinal content(gm)	% of inhibition
Control	0.67 ± 0.21	-------	0.78 ± 0.16	-------
Loperamide 3 mg/kg	0.12 ± 0.08a**	82.1	0.21 ± 0.08a**	73.08
CF300mg/kg	0.18 ± 0.054a*	73.13	0.27 ± 0.09a**	65.38
CF400mg/kg	0.17 ± 0.03a*	74.6	0.269 ± 0.06a**	65.51
CF500mg/kg	0.16 ± 0.04a**	76.12	0.248 ± 0.04a**	68.21
Control	0.77 ± 0.17	-------	0.83 ± 0.2	-------
Loperamide 3 mg/kg	0.12 ± 0.08a***	84.41	0.21 ± 0.078a**	74.70
MF300mg/kg	0.30 ± 0.05a*	61.04	0.36 ± 0.11a*	56.63
MF400mg/kg	0.20 ± 0.04a**	74.03	0.31 ± 0.04a*	62.65
MF500mg/kg	0.19 ± 0.02a**	75.32	0.29 ± 0.03a*	65.06
Control	0.47 ± 0.06	-------	0.45 ± 0.07	-------
Loperamide 3 mg/kg	0.083 ± 0.01a**c*d*e*f*	82.34	0.08 ± 0.01a*c*d*e*f*	82
AF300mg/kg	0.43 ± 0.098b*	8.5	0.44 ± 0.08b*	2.22
AF400mg/kg	0.38 ± 0.07b*	19.12	0.43 ± 0.12b*	4.44
AF500mg/kg	0.362 ± 0.09b*	22.98	0.422 ± 0.09b*	6.22
AF1000mg/kg	0.35 ± 0.06b*	25.53	0.41 ± 0.05b*	8.89

Values are expressed as Mean ± S.E.M (n = 6), analysis was performed with One-Way ANOVA followed by Tukey test;^a compared to control,^b to standard drug,^c to 300 mg/kg,^d to 400 mg/kg,^e to 500 mg/kg,^f to 1000 mg/kg,^g to CF300 mg/kg,^h to CF 400 mg/kg and^I to CF500 mg/kg; *P <0.05, **P <0.01, ***P <0.001; CF chloroform fraction, MF methanol fraction, AF aqueous fraction. Negative controls were treated with the vehicle used for reconstitution (2 % v/v Tween 80 for the chloroform and methanol fractions or distilled water for the aqueous fraction) orally