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. 2016 Sep 29;17:139. doi: 10.1186/s12882-016-0352-1

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — The production of fibronectin (Fn) by HK-2 cells stimulated with recombinant CCL18 for 48 h in a diabetic milieu. A significantly higher concentration of Fn was produced by HK-2 cells stimulated with recombinant CCL18 in high concentration of glucose in comparison to CCL18 only or high glucose concentration only. P < 0.001. Key: N0 = physiological glucose, A0 = glycated albumin, M0 = mannitol, H0 = high glucose, N20 = physiological glucose + 20 ng/ml CCL18, A20 = glycated albumin + 20 ng/ml CCL18, M20 = mannitol + 20 ng/ml CCL18, H20 = high glucose + 20 ng/ml CCL18