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. 2016 May 26;44(17):8097–8111. doi: 10.1093/nar/gkw467

Figure 9.

Figure 9.

Model of association of HNF1β to mitotic chromatin. The localization of HNF1β on mitotic chromatin may be considered to be based on a two-step process. In the first step, RAN-GTP gradient and Importin-β system could bring HNF1β in close proximity to mitotic chromatin. In the second step, the DNA-binding ability of HNF1β could provide a more intimate and stable association of the protein with mitotic chromatin.