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. 2016 Jun 27;44(17):8189–8198. doi: 10.1093/nar/gkw527

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Published by Oxford University Press on behalf of Nucleic Acids Research 2016. This work is written by (a) US Government employee(s) and is in the public domain in the US.

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Figure 2. — Examples of complex MYC locus rearrangements in three MMCL. (A) Insertion of chr11 (not including CCND1) and chr14 (IG SE) sequences between flanking duplicated sequences (cross-hatched) on chr8 in KMS-12 MMCL; (B) Insertion of chr8, 11 and 14 sequences between flanking duplicated sequences on chr4 in MOLP-8 MMCL; (C) Insertion of chr8 and chr2 sequences between flanking duplicated sequences containing chr22 and chr16 sequences from a der(16)t(16;22) translocation in 8226 MMCL; (D) Interphase FISH showing insertion of chr14 CH (IGH SE) probe (green) between duplicated chr4 sequences (C7 probe [Supplementary Table S5], red).