Table 1. Tandem duplications, reciprocal interchromosomal rearrangements and reciprocal inversions in eight MMCLs.
MMCL | TD | Interchromosomal rearrangements | Inversions | ||||||
---|---|---|---|---|---|---|---|---|---|
Total | CNG × 2 | CNG × 1 | CNG + CNL | CNL × 2 | Total | CNG × 2 | CNG × 1 | ||
AMO | 9 | 10 | 1 | ||||||
INA6 | 5 | 1 | 1 | ||||||
JIM3 | 72 | 17 | 1 | 5 | 1 | ||||
JJN3 | 29 | 7 | 4 | 1 | 1 | 2 | 1 | ||
KP6 | 8 | 4 | 4 | ||||||
MOLP8 | 12 | 10 | 2 | 1 | 1 | ||||
XG2 | 21 | 7 | 3 | 3 | 1 | 1 | |||
XG6 | 6 | 5 | 1 | 2 | |||||
TOTAL | 162 | 61 | 14 | 2 | 2 | 2 | 13 | 3 | 1 |
TD = tandem duplication.
CNG = copy number gain; CNL = copy number loss.
CNG × 2 = insertion with flanking duplicated sequences OR translocation with duplicated sequences from both donor breakpoints at both breakpoint junctions.