Table 2. Reciprocal interchromosomal rearrangements in 25 MM tumors.
Tumor | Primary IGH | Other interchromosomal rearrangements | |||||
---|---|---|---|---|---|---|---|
samples | Total | CNG × 2 | CNG × 1 | CNG + CNL | CNL × 1 | CNL × 2 | |
A1855 | 11;14 | 0 | |||||
A1864 | 11:14(der14) | 0 | |||||
A1868 | 8 | 1 | 1 | 1 | 4 | ||
A1886 | 1 | 1 | |||||
A1892 | 1 | 1 | |||||
A1898 | 4 | (2)a | 1 | 1 | |||
A1904 | 2 | 2 | |||||
A1910 | 2 | 2 | |||||
A1916 | 2 | 1 | 1 | ||||
A1922 | 1 | 1 | |||||
A1928 | 6 | 2 | 1 | 3 | |||
A1934 | 11;14(der14) | 0 | |||||
A1940 | 2 | 2 | |||||
A1946 | 3 | 1 | 2 | ||||
A1952 | 11;14(der14) | 0 | |||||
A1958 | 14;16 | 2 | |||||
A1964 | 11;14 | 0 | |||||
A1970 | 1 | 1 | |||||
A1976 | 4;14 | 1 | 1 | ||||
A1982 | 11;14(der14) | 0 | |||||
A1988 | 1 | 1 | |||||
A1994 | 11;14 | 0 | |||||
A2066 | 11;14 | 2 | 2 | ||||
A2070 | 11;14 | 2 | 1 | 1 | |||
A2079 | 4;14 | 1 | 1 | ||||
TOTAL | 42 | 13(15) | 5 | 13 | 6 | 0 |
CNG (CNL) = copy number gain (loss) >1 kb and <4 Mb.
CNGX2 = insertion with flanking duplicated sequences OR translocation with sequences from both chromosome breakpoints at both breakpoint junctions.
aTwo rearrangements with CNG > 4 Mb included in parentheses.