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. 2016 Aug 26;44(17):8052–8064. doi: 10.1093/nar/gkw725

Table 2. The limits of detection (LOD) of anti-VEGF165 aptamers (AF83-7 versus AF83-1).

Aptamers for VEGF-165 Aptamer ID KD (pM) LOD (M)a LOD (pg/ml)a
Aptamer modified with a single PS2 AF83-7 1 ± 0.1 ≤10 × 10−15 ≤0.38
Native aptamer AF83-1 961 ± 25 ≤0.1 × 10−9 ≤3800

aLOD values are expressed as median, n = 6.