Table 2. The limits of detection (LOD) of anti-VEGF165 aptamers (AF83-7 versus AF83-1).
Aptamers for VEGF-165 | Aptamer ID | KD (pM) | LOD (M)a | LOD (pg/ml)a |
---|---|---|---|---|
Aptamer modified with a single PS2 | AF83-7 | 1 ± 0.1 | ≤10 × 10−15 | ≤0.38 |
Native aptamer | AF83-1 | 961 ± 25 | ≤0.1 × 10−9 | ≤3800 |
aLOD values are expressed as median, n = 6.