Figure 7. PHA767491 alters the subcellular distribution of CDK9₄₂ and CDK9₅₅ in CD4⁺ T cells.

Immunofluorescence staining for changes in the expression of CDK9₄₂ and CDK9₅₅ in alloantigen-activated CD4⁺ T cells pretreated with PBS or 3 μM PHA767491. Scale bar: 5 mm. Cell nuclei were identified by DAPI staining (blue). PHA767491 pretreatment abrogated alloantigen-induced up-regulation of CDK9₄₂ expression, but preserved CDK9₅₅ expression. All data are representative of three independent experiments (n = 4).