Table 2. Univariate survival analysis for overall survival and disease free survival in patients with esophageal cancer.
| Prognostic factor | Overall survival | Disease free survival | ||||
|---|---|---|---|---|---|---|
| Mean(m) | HR(95%CI) | P | Mean(m) | HR(95%CI) | P | |
| Age | 1.22(1.07-1.40) | 0.003 | 1.12(0.99-1.27) | 0.079 | ||
| ≤58 years | 72.8 | 66.1 | ||||
| >58 years | 60.2 | 57.2 | ||||
| Gender | 0.73(0.60-0.83) | <0.001 | 0.75(0.64-0.88) | <0.001 | ||
| Males | 63.3 | 59.1 | ||||
| Females | 78.0 | 71.4 | ||||
| pT category | 1.85(1.58-2.16) | <0.001 | 1.87(1.60-2.17) | <0.001 | ||
| T1-2 | 86.7 | 83.0 | ||||
| T3-4 | 58.1 | 52.9 | ||||
| pN category | 2.70(2.36-3.1) | <0.001 | 2.72(2.38-3.11) | <0.001 | ||
| N0 | 89.3 | 85.1 | ||||
| N1-3 | 42.1 | 37.0 | ||||
| Differentiation | 1.53(1.33-1.75) | <0.001 | 1.50(1.32-1.71) | <0.001 | ||
| G1 | 73.5 | 68.7 | ||||
| G2-3 | 54.2 | 49.4 | ||||
| Tumor location | 1.10(1.02-1.19) | 0.013 | 1.10(1.02-1.18) | 0.012 | ||
| Upper | 64.7 | 61.1 | ||||
| Middle | 71.3 | 65.7 | ||||
| Lower | 61.4 | 58.0 | ||||
| EGJ | 41.2 | 36.6 | ||||
| Weight loss | 1.25(1.10-1.43) | 0.001 | 1.22(1.07-1.39) | 0.002 | ||
| No | 72.3 | 67.2 | ||||
| Yes | 61.2 | 56.8 | ||||
| Smoking | 1.31(1.14-1.51) | <0.001 | 1.28(1.11-1.46) | <0.001 | ||
| Never | 73.8 | 68.5 | ||||
| Ever (former + current) | 62.3 | 57.9 | ||||
| Alcohol | 1.39(1.21-1.60) | <0.001 | 1.36(1.19-1.56) | <0.001 | ||
| Never | 72.4 | 67.1 | ||||
| Ever (former + current) | 54.8 | 50.8 | ||||
| Fibrinogen level | 1.47(1.28-1.69) | <0.001 | 1.41(1.23-1.61) | <0.001 | ||
| Normal level | 73.3 | 68.1 | ||||
| Hyperfibrinogenemia | 53.5 | 50.0 | ||||
Abbreviations: EGJ, esophagogastric junction; G, grade; HR, hazard ratio; 95% CI, 95% confidence interval
Bold values are statistically significant (P < 0.05).