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. 2016 Mar 24;7(18):25585–25592. doi: 10.18632/oncotarget.8339

Table 2. Univariate and multivariate Cox proportional hazards analysis of FOX gene expression and overall survival for patients with gastric cancer in the TCGA cohort.

Univariate analysis Multivariate analysis
Factor HR (95% CI) P HR (95% CI) P
Gender 0.681 (0.457–1.016) 0.060
Age 1.020 (0.585–1.792) 0.014 1.036 (1.016–1.055) < 0.001
T category 1.375 (1.094–1.727) 0.007 1.326 (1.028–1.709) 0.030
N stage 1.300 (1.113–1.518) 0.001 1.271 (1.077–1.500) 0.005
M stage 1.590 (1.132–2.234) 0.007 1.384 (0.978–1.959) 0.066
Grade 1.313 (0.933–1.848) 0.119
Tumor location 0.971 (0.828–1.139) 0.721
FOXA1 0.985 (0.870–1.116) 0.815
FOXA2 0.979 (0.864–1.111) 0.746
FOXA3 0.884 (0.773–1.013) 0.078
FOXC1 0.986 (0.845–1.152) 0.862
FOXC2 1.139 (0.899–1.442) 0.282
FOXD1 0.955 (0.824–1.106) 0.536
FOXD2 0.818 (0.640–1.044) 0.107
FOXD3 1.419 (1.007–1.999) 0.045 1.704 (1.212–2.397) 0.002
FOXD4 0.564 (0.284–1.117) 0.101
FOXF1 1.066 (0.923–1.239) 0.370
FOXF2 0.990 (0.848–1.157) 0.903
FOXH1 1.067 (0.861–1.323) 0.552
FOXI1 0.694 (0.413–1.164) 0.167
FOXJ1 0.971 (0.866–1.089) 0.616
FOXJ2 0.980 (0.668–1.438) 0.919
FOXJ3 0.897 (0.613–1.313) 0.575
FOXK1 1.001 (0.751–1.336) 0.989
FOXK2 0.972 (0.657–1.437) 0.887
FOXL1 1.138 (0.882–1.468) 0.320
FOXL2 0.998 (0.639–1.559) 0.994
FOXM1 1.000 (0.835–1.197) 0.998
FOXN2 0.948 (0.665–1.350) 0.767
FOXN3 1.179 (0.913–.522) 0.208
FOXO1 1.008 (0.753–1.349) 0.958
FOXO3 1.174 (0.891–1.547) 0.255
FOXO4 0.681 (0.513–0.904) 0.008 0.613 (0.452–0.832) 0.002
FOXP1 1.018 (0.751–1.380) 0.910
FOXP2 1.144 (0.961–1.362) 0.131
FOXP3 0.807 (0.629–1.035) 0.092
FOXP4 0.938 (0.747–1.177) 0.581
FOXQ1 0.919 (0.817–1.035) 0.165
FOXS1 1.219 (1.008–1.474) 0.041 1.180 (0.957–1.455) 0.121

Abbreviations: CI, confidence interval; HR, hazard ratio.

Bold type indicates statistical significance.