Figure 4. Combination of pathway crosstalk information and miRNA can gain the power for predicting survival of glioma patients.
A. Combination of crosstalk pathways of core module in Figure 3C and miRNAs for prediction the survival of overall glioma patients. The upper panel is the expression pattern of genes and miRNAs for predicting survival and the survival time distribution of all the glioma samples. The bottom panel is the estimates of survival of glioma samples based on signature genes of pathways that involved in the core module in Figure 3C and miRNAs that regulated them. B. Only signature genes involved in the crosstalk pathway module used for estimating patient survival. C. Only signature miRNAs which regulated these crosstalk pathways used for estimating patient survival.