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. 2016 Mar 22;7(18):25791–25800. doi: 10.18632/oncotarget.8268

Table 3. Meta-regression for the potential source of heterogeneity.

Study characteristic P-value RDOR 95% CI
Specimen type (plasma, serum or tissue) 0.0587 0.56 (0.31-1.02)
Control sources (healthy blood, normal tissue or adjacent non-tumor tissue) 0.9385 0.90 (0.05-15.68)
Sample size (GC<100 vs. GC≥100) 0.1047 2.27 (0.82-6.23)
Reference gene (GAPDH vs. β-actin) 0.5264 0.73 (0.25-2.13)
Cut-off value (value <100 vs. value ≥100) 0.1798 0.71 (0.42-1.2)
Study quality (QUADAS score≤10 or≥11) 0.1008 3.29 (0.76-14.14)

Abbreviations: CI: confidence interval; RDOR: relative diagnostic odds ratio; QUADAS: quality assessment for studies of diagnostic accuracy; GC: Gastric cancer; GAPDH: glyceraldehyde-phosphate dehydrogenase