Table 3. HMGA2 protein expression by immunohistochemistry in 19 paired esophageal squamous cell carcinomas (ESCC) and in 10 esophageal adenocarcinomas (EAC).

HMGA2 Staining Score n (%)
Histological Type	0	1+	2+	3+	4+
ESCC Normal Surrounding Tissue (n=19)	18(95)	0	0	0	1(5)
ESCC (n=19)	3(16) *	6(32)	2(10)	2(10)	6(32)
EAC (n=10)	1(10)	4(40)	1(10)	2(20)	2(20)

^*Statistically significant difference (p ≤ 0.0001) in ESCC HMGA2 expression when compared to their respective histologically normal surrounding mucosa (t-Student test).