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. 2016 Mar 24;7(18):26181–26191. doi: 10.18632/oncotarget.8325

Figure 4. Treatment of the PDXs derived from Patient 2 with chemotherapeutic drugs.

Figure 4

The PDX line #2BC A, C. was obtained from the Patient 2′s sample before her treatment with platinum-based chemotherapy. The PDX line #2PC B, D. was obtained from a sample of the same Patient 2 at surgery performed after 3 cycles of platinum-based chemotherapy. Panels A and B show the treatment of each cohort of 6 mice as indicated. Panels C and D show the response to the prolonged treatment with PLD of the PDX cohorts derived from the two samples, before (#2BC) and after (#2PC) chemotherapy. Day 0 represent the beginning of mice treatment. Treatment details are reported in the Materials and Methods section.