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. 2016 Mar 24;7(18):26181–26191. doi: 10.18632/oncotarget.8325

Figure 5. Expression of TOP2A protein in the PDXs.

Figure 5

A. Representative images showing the immunohistochemical detection of TOP2A protein in the indicated PDX line. Bars: 50 μm. B. Percentage of cells showing detectable staining with TOP2A antibody, measured using the NIH ImageJ software. The TOP2A signal was estimated by the ratio between the area occupied by positive cells and the total area occupied by cancer cells in the same field. Statistical significance was determined using ANOVA test. **P < 0.01.