Figure 5. Gli2, FoxM1 and KIF20A are highly expressed in HCC tissues.
(A) IHC detection of Gli2, FoxM1 and KIF20A expression in a representative HCC sample and a matched adjacent normal liver tissue sample. The areas of carcinoma and adjacent tissues were sketched. Subcellular locations of Gli2, FoxM1 and KIF20A were indicated by yellow arrows. (B) The expression of Gli2, FoxM1 and KIF20A was plotted using the immunohistochemical scores. Statistical significance was analyzed using the Wilcoxon matched-pairs signed-rank test. (C) Eight pairs of randomly selected HCC tissues and adjacent non-tumor tissues were subjected to Western blot analysis for Gli2, KIF20A and FoxM1.