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. 2016 Mar 30;7(18):26388–26399. doi: 10.18632/oncotarget.8506

Figure 6. Caspase-2 expression is correlated with tumor grade in glioma.

Figure 6

(A) Representative images of immunohistochemical staining of caspase-2 proteins in glioma tissue sections (200 ×). Yellow arrow indicates typical staining. (B) Percentage of caspase-2 positive expression in low-grade (grades I and II) and high-grade (grades III and IV) glioma carcinoma specimens as analyzed by immunohistochemistry on a human glioma tissue microarray (N = 72). (C) Percentage of caspase-2 positive (+) expression in miR-149 positive glioma carcinoma subgroups (N = 57). (D) Immunohistochemistry showing percentage of moderate miR-149 expression (+) and strong miR-149 expression (++) in low-grade (grades I and II) and high-grade (grades III and IV) glioma carcinoma subgroups (N = 57). **p < 0.01.