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. 2016 Mar 28;7(18):26465–26479. doi: 10.18632/oncotarget.8417

Figure 2. RET over-expression in MCF7 is due to transcriptional mechanisms.

Figure 2

A. Quantification of RET genomic content in MCF7 and T47D by using two amplimers designed in the 5′ and 3′ UTRs respectively. Thresholds to detect DNA deletion or duplication were settled to 0.5 and 1.5 of % genomic DNA compared to a reference genome, respectively. B. Quantification of RET mRNA half-life by DRB pulse chase experiments in MCF7 and T47D. Log-linear regression curves are shown. Values are the mean ±SD of at least two independent experiments performed in triplicate.