Figure 4. miR-520g increased chemoresistance to cisplatin and paclitaxel.

(A) Annexin V/PI staining followed by FACS analysis showed that miR-520g overexpression in A2780 cisplatin resistant (A2780RC) and sensitive (A2780SC) cells increased chemoresistance to cisplatin and inhibited apoptosis (*p < 0.05). (B) miR-520g overexpression in A2780 paclitaxel resistant (A2780RP) and sensitive (A2780SP) cells increased chemoresistance to paclitaxel and inhibited apoptosis (*p < 0.05). (C) miR-520g levels in A2780 cisplatin and paclitaxel resistant/sensitive cell lines (*p < 0.05).