Table 1. Association between expression of PBK/TOPK and clinical characteristics in 185 NPC patients.

Characteristics	No.	PBK/TOPK expression		P value (Chi-square test)
		Low	High
Gender
Male	142	73	69	0.574
Female	43	20	23
Age
<45	96	48	48	0.939
≥45	89	45	44
T stage
T1-2	56	35	21	0.028
T3-4	129	58	71
N stage
N0-1	104	57	47	0.162
N2-3	81	36	45
M stage
M0	169	89	80	0.838
M1	16	8	8
Clinical stage
I-II	22	14	8	0.182
III-IV	163	79	84
Death
Yes	49	17	32	0.011
No	136	76	60
Disease progression
Yes	24	6	18	0.008
No	161	87	74
WHO histological classification Type 2
Differentiated	15	8	7	0.942
Undifferentiated	169	89	81

Abbreviations: WHO, World Health Organization