Table 5. Univariate and multivariate analyses of overall survival in esophageal carcinoma (FCEP status).

Variable	Univariate analyses			Multivariate analyses
	HR	95% CI	P-value	HR	95% CI	P-value
FCEP status	0.452	0.260–0.787	0.005a	0.460	0.260–0.813	0.008a
Histological grade	1.701	1.229–2.356	0.001a	1.508	1.050–2.166	0.026a
Age	1.101	0.700–1.734	0.677	1.062	0.639–1.765	0.817
Sex	0.954	0.541–1.680	0.869	1.262	0.668–2.383	0.473
Length	1.179	0.741–1.877	0.488	1.161	0.683–1.975	0.582
Location	1.153	0.774–1.718	0.483	1.123	0.759–1.662	0.560
T	2.368	1.323–4.237	0.004a	1.878	0.860–4.097	0.114
N	2.811	1.766–4.474	<0.001a	2.052	0.830–5.072	0.119
M	2.312	0.933–5.731	0.07	1.746	0.539–5.657	0.353
TNM	3.368	2.130–5.324	<0.001a	1.294	0.475–3.522	0.614

Abbreviations: HR, hazard ratio; CI, confidence interval; FCEP, favourable CTLA-4 expression profile; TNM, tumor, node, metastasis.

^aP < 0.05.