Table 2. MALDI-TOF-TOF results of the differentially expressed proteins.
Spot No. | Protein description | Gene name | Function | Accession no. | Theoretical Mw/pI | Score | C.I.% | Expr. level (K562 vs K562/ADM) |
---|---|---|---|---|---|---|---|---|
1 | Complement component 1 Q subcomponent-binding protein | C1QBP | Cell apoptosis, proliferation and migration | IPI00014230 | 31741.8/4.74 | 282 | 100 | + |
2 | Lactoylglutathione lyase | GLO1 | Metabolism | IPI00220766 | 20992.3/5.12 | 523 | 100 | + |
3 | Galectin-1 | LGALS1 | Cell apoptosis, proliferation and differentiation | IPI00219219 | 15048.3/5.34 | 295 | 100 | + |
4 | Sorcin isoform b | SRI | Calcium-binding protein | IPI00414264 | 20616.9/ 5.11 | 150 | 100 | + |
5 | Isoform 2 of Proteasome subunit alpha type-3 | PSMA3 | Proteolysis | IPI00171199 | 27857.8/5.19 | 349 | 100 | + |
6 | Isoform 2 of Heterogeneous nuclear ribonucleoprotein D-like | HNRPDL | Cellular transcription | IPI00845282 | 33739.2/6.85 | 290 | 100 | - |
7 | Proteasome subunit alpha type-2 | PSMA2 | Proteolysis | IPI00219622 | 25996.3/6.92 | 259 | 100 | - |
8 | Isoform 2 of Transcription factor BTF3 | BTF3 | Cellular transcription | IPI00419473 | 17688.2/6.85 | 185 | 100 | - |
9 | Poly(rC)-binding protein 1 | PCBP1 | Signal transduction | IPI00016610 | 37987.1/6.66 | 526 | 100 | - |
10 | Isoform A2 Heterogeneous nuclear ribonucleoproteins A2/B1 | HNRNPA2B1 | Cellular transcription | IPI00414696 | 36040.9/8.67 | 714 | 100 | - |
11 | Eukaryotic translation initiation factor 3 subunit I | EIF3I | Signal transduction | IPI00012795 | 36478.6/5.38 | 300 | 100 | + |