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. 2016 Mar 30;7(18):26724–26738. doi: 10.18632/oncotarget.8494

Figure 2. Evaluation of template noise in cell free DNA and cells enriched from blood as measured by SNV-SF Circulating epithelial cell DNA (cecDNA) or matched cell free DNA was recovered from 29 normal healthy donors.

Figure 2

Paired template were sequenced using the AmpliSeq library and compared to germline sequence from the same sample. Alterations with an extended reportable range to include all evaluated bases in the library were enumerated. A two-tailed Wilcoxon rank sum test measured a mean difference of 3.0 and a p value of 0.0009.