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. 2016 Mar 30;7(18):26751–26764. doi: 10.18632/oncotarget.8495

Table 1. Relationship between MIA or STOX2 expression and clinicopathological parameters in OSCCs.

Parameters MIA STOX2
negative positive negative positive
Gender
 Male 80 55 93 42
 Female 37 30 51 16
P value 0.6504 0.3242
Age
 <-65 46 36 57 25
 >65 71 49 87 33
P value 0.6666 0.7517
Site
 Tongue 55 41 68 28
 Gingiva 38 32 49 21
 Other 24 12 27 9
P value 0.3713 0.8569
Histological differentiation*
 Well 54 45 63 36
 Moderately 50 34 66 18
 Poorly 13 6 15 4
P value 0.4939 0.0622
T classification
 Tis, T1 14 11 14 11
 T2 29 22 38 13
 T3 44 19 44 19
 T4 30 33 48 15
P value 0.0906 0.2705
Clinical stage
 I 14 11 14 11
 II 29 16 37 8
 III 41 20 43 18
 IV 33 38 50 21
P value 0.0786 0.1370
Nodal metastasis
 Negative 92 34 102 24
 Positive 25 51 42 34
P value < 0.0001 0.0002
MIA
 Negative - - 102 15
 Positive - - 42 43
P value - <0.0001

Relationship between STOX2 expression and each parameters were calculated by χ2 test or Fisher's exact test. T classification and clinical stage were classified according to the TNM classification.