Table 1. Relationship between MIA or STOX2 expression and clinicopathological parameters in OSCCs.
| Parameters | MIA | STOX2 | ||
|---|---|---|---|---|
| negative | positive | negative | positive | |
| Gender | ||||
| Male | 80 | 55 | 93 | 42 |
| Female | 37 | 30 | 51 | 16 |
| P value | 0.6504 | 0.3242 | ||
| Age | ||||
| <-65 | 46 | 36 | 57 | 25 |
| >65 | 71 | 49 | 87 | 33 |
| P value | 0.6666 | 0.7517 | ||
| Site | ||||
| Tongue | 55 | 41 | 68 | 28 |
| Gingiva | 38 | 32 | 49 | 21 |
| Other | 24 | 12 | 27 | 9 |
| P value | 0.3713 | 0.8569 | ||
| Histological differentiation* | ||||
| Well | 54 | 45 | 63 | 36 |
| Moderately | 50 | 34 | 66 | 18 |
| Poorly | 13 | 6 | 15 | 4 |
| P value | 0.4939 | 0.0622 | ||
| T classification | ||||
| Tis, T1 | 14 | 11 | 14 | 11 |
| T2 | 29 | 22 | 38 | 13 |
| T3 | 44 | 19 | 44 | 19 |
| T4 | 30 | 33 | 48 | 15 |
| P value | 0.0906 | 0.2705 | ||
| Clinical stage | ||||
| I | 14 | 11 | 14 | 11 |
| II | 29 | 16 | 37 | 8 |
| III | 41 | 20 | 43 | 18 |
| IV | 33 | 38 | 50 | 21 |
| P value | 0.0786 | 0.1370 | ||
| Nodal metastasis | ||||
| Negative | 92 | 34 | 102 | 24 |
| Positive | 25 | 51 | 42 | 34 |
| P value | < 0.0001 | 0.0002 | ||
| MIA | ||||
| Negative | - | - | 102 | 15 |
| Positive | - | - | 42 | 43 |
| P value | - | <0.0001 | ||
Relationship between STOX2 expression and each parameters were calculated by χ2 test or Fisher's exact test. T classification and clinical stage were classified according to the TNM classification.