Table 2. Univariate and multivariate analysis of disease free survival.
| Parameters | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Gender | ||||||
| M | 1.00 | |||||
| F | 1.2081 | 0.7318–1.9571 | 0.4526 | |||
| Age | ||||||
| ≤65 | 1.00 | |||||
| >65 | 0.8406 | 0.5215–1.3705 | 0.4812 | |||
| Site | ||||||
| Tongue | 1.00 | |||||
| Other | 1.1741 | 0.7290–1.9081 | 0.5100 | |||
| Histology | ||||||
| Well | 1.00 | |||||
| Mod, Por | 0.8258 | 0.5105–1.3300 | 0.4307 | |||
| T factor | ||||||
| Tis-3 | 1.00 | 1.00 | ||||
| T4 | 1.9362 | 1.2021–3.1397 | 0.0067 | 1.4427 | 0.8294–2.5103 | 0.1938 |
| Clinical stage | ||||||
| I–III | 1.00 | |||||
| IV | 1.5797 | 0.9738–2.5453 | 0.0638 | |||
| Nodal metastasis | ||||||
| Negative | 1.00 | 1.00 | ||||
| Positive | 1.8821 | 1.1667–3.0363 | 0.0098 | 1.1509 | 0.6142–2.1261 | 0.6576 |
| MIA | ||||||
| Negative | 1.00 | 1.00 | ||||
| Positive | 2.1513 | 1.3219–3.4696 | 0.0023 | 6.7357 | 1.4118–120.716 | 0.0114 |
| STOX2 | ||||||
| Negative | 1.00 | 1.00 | ||||
| Positive | 1.9418 | 1.1868–3.1336 | 0.0088 | 1.8507 | 1.0457–3.2264 | 0.0449 |
Univariate and multivariate analysis was calculated by means of Cox proportional hazard model. HR and 95% CI mean hazard ratio and 95% confidence intervals, respectively.