Table 1. Multivariate analysis with Cox proportional hazards model for overall survival.
Factor | Total cases (n = 122) | |||
---|---|---|---|---|
Univariate analysis | Multivariate analysis | |||
Risk ratio label (95% confidence interval) | P | Risk ratio label (95% confidence interval) | P | |
MMP10 high (score 2) | 3.30 (1.67–6.51) | 0.001** | 2.39 (1.19–4.80) | 0.014* |
Advanced age (over 50) | 1.78 (0.82–3.87) | 0.14 | ||
Multipara (≥ 2) | 1.78 (0.70–3.24) | 0.12 | ||
Histological subtype | ||||
Serous | 1.55 (0.82–2.92) | 0.17 | ||
Cleacell | 0.81 (0.40–1.63) | 0.55 | ||
Endometrioid | 0.50 (0.16–1.64) | 0.26 | ||
Mucinous | 0.97 (0.23–4.02) | 0.97 | ||
Advanced Stage (over FIGO Stage III) | 8.02 (2.85–22.59) | < 0.001** | ||
Peritoneal dissemination | 4.73 (1.93–9.90) | < 0.001** | ||
Lymph node metastasis | 1.48 (0.78–2.81) | 0.23 | ||
Platinum resistant | 12.46 (5.18–29.96) | < 0.001** | 5.75 (2.09–15.81) | 0.001** |
Nonoptimal debulking surgery | 7.00 (3.33–14.74) | < 0.001** | 2.84 (1.21–6.64) | 0.016* |
Factor | Advanced cases (n = 74) | |||
---|---|---|---|---|
Univariate analysis | Multivariate analysis | |||
Risk ratio label (95% confidence interval) | P | Risk ratio label (95% confidence interval) | P | |
MMP10 high (score 2) | 2.98 (1.46–6.09) | 0.003** | 2.98 (1.46–6.12) | 0.003** |
Advanced age (over 50) | 1.38 (0.60–3.16) | 0.44 | ||
Multipara (≥ 2) | 1.89 (0.83–3.65) | 0.14 | ||
Histological subtype | ||||
Serous | 0.67 (0.34–1.32) | 0.24 | ||
Cleacell | 2.01 (0.91–4.43) | 0.083 | ||
Endometrioid | 0.68 (0.21–2.24) | 0.53 | ||
Mucinous | 1.81 (0.43–7.65) | 0.42 | ||
Advanced Stage (over FIGO Stage III) | – | – | ||
Peritoneal dissemination | – | – | ||
Lymph node metastasis | – | – | ||
Platinum resistant | 3.93 (1.62–9.54) | 0.001** | ||
Nonoptimal debulking surgery | 4.71 (1.83–12.14) | 0.001** | 4.70 (1.82–12.13) | 0.001** |
Factors correlated with deciding FIGO stages were excluded from advanced case's table. The other absent columns are excluded from final model by step wise method (*P < 0.05, **P < 0.01).