Fig. 5.

Membrane permeabilization: arginine confers eCAP resistance to divalent cations compared with lysine. P. aeruginosa (left) and MRSA (right) were treated with 1 µM WK12 and WR12 in PBS and in the presence or absence of divalent cations (2mM each); the data are normalized with respect to eCAP-specific permeabilization in saline alone; an asterisk indicates a statistically significant difference (P < 0.05) between WR12 and WK12 for three independent experimental trials performed in triplicate.