Table 1. Primary sequences, molecular masses and hydrophobic moments of eCAPs in order of increasing length .
Previously designed (WR series) cationic peptides were modified to WK peptides via global Arg-to-Lys substitutions; hydrophobic moments were examined using the online program Heliquest (http://heliquest.ipmc.cnrs.fr/).
| Peptide sequence | Name | Charge | Molecular mass (Da) | Hydrophobic moment (μH) |
|---|---|---|---|---|
| WWRRWWRR | WR8 | +4 | 1390 | 0.93 |
| WWKKWWKK | WK8 | +4 | 1280 | 0.93 |
| WRWWRRWWRR | WR10 | +5 | 1730 | 0.94 |
| WKWWKKWWKK | WK10 | +5 | 1590 | 0.94 |
| RWWRWWRRWWRR | WR12 | +6 | 2070 | 0.99 |
| KWWKWWKKWWKK | WK12 | +6 | 1900 | 0.99 |
| WRRWWRWWRRWWRR | WR14 | +7 | 2410 | 1.03 |
| WKKWWKWWKKWWKK | WK14 | +7 | 2220 | 1.03 |
| RWWRRWWRWWRRWWRR | WR16 | +8 | 2760 | 1.02 |
| KWWKKWWKWWKKWWKK | WK16 | +8 | 2530 | 1.02 |
| WRRWWRRWWRWWRRWWRR | WR18 | +9 | 3100 | 1.04 |
| WKKWWKKWWKWWKKWWKK | WK18 | +9 | 2850 | 1.04 |