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. 2016 Sep 29;26:16068. doi: 10.1038/npjpcrm.2016.68

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Copyright © 2016 The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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WISDOM: probability of moderate or severe exacerbations over 54 weeks in patients with severe-to-very-severe COPD (FEV₁<50% predicted) and ⩾1 exacerbation in the year prior to screening.³² Hazard ratio is for ICS withdrawal versus ICS continuation. CI, confidence interval; ICS, inhaled corticosteroid. Reproduced from New England Journal of Medicine.⁶¹ Copyright © (2014) Massachusetts Medical Society. Reprinted with permission from Massachusetts Medical Society.