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. 2016 Sep 29;26:16068. doi: 10.1038/npjpcrm.2016.68

Figure 4.

Figure 4

WISDOM: adjusted mean change in FEV1 in patients with severe-to-very-severe COPD (FEV1 <50% predicted) and ⩾1 exacerbation in the year prior to screening.32 Adjusted mean change in FEV1 during the 52-week study period in WISDOM. FEV1, forced expiratory volume in 1 s; ICS, inhaled corticosteroid. Reproduced from New England Journal of Medicine.61 Copyright © (2014) Massachusetts Medical Society. Reprinted with permission from Massachusetts Medical Society.