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. 2016 Jun 3;10(12):2844–2853. doi: 10.1038/ismej.2016.80

Figure 2.

Figure 2

Mutations identified on the genome of 10 clones isolated from a working syntrophic co-culture (clones initially labeled as DvH-s 1–5) and from the wild-type DvH population (clones initially labeled as DvH-ns 1–5). Each square represents an SNP (green) or INDEL (brown), as identified by comparing the genome sequence of the corresponding clone with the reference DvH genome. The color scale of each square encodes the proportion of reads that contain the corresponding SNP or INDEL. The genomic location of each mutation is shown at the top. In total, 26 SNPs and 27 INDELs were identified on the chromosome. An additional two SNPs and two INDELs were identified on the megaplasmid that are not shown in this figure (but included in the Supplementary File 1). As discussed in the main text, 2 out of the 57 mutations were present in all seven ‘co-culturable' clones (DvH-s 1–5, DvH-ns 1 and DvH-ns2), a synonymous point mutation in the gene DVU3023 and a disruptive INDEL in the gene DVU2287.