Table 2. Summary of relevant clinical and pathological features of patients with LCT.
| Parameter | Mean, years (range) | |
|---|---|---|
| Age at onset of symptoms | 56 (15–99) | |
| Age at biopsy-confirmed diagnosis of MF | 60 (22–99) | |
| Age at development of tumour-stage MF | 64 (22–102) | |
| Age at LCT of MF | 63 (25–102) | |
|
| ||
| Parameter | n/Total | % |
|
| ||
| Sex | ||
| Female | 24 | 47 |
| Male | 27 | 53 |
| Race | ||
| Causasian | 44 | 88 |
| Black | 3 | 6 |
| Asian | 3 | 6 |
| Number of patients who developed tumour stage disease in skin | 39/51 | 76 |
| Number of patients DOD | 24/51 | 47 |
| Thickest stage = tumour | ||
| Ever | 34/50 | 68 |
| At LCT | 24/42 | 57 |
| Involvement of subcutis | ||
| Ever | 17/47 | 36 |
| At LCT | 11/37 | 30 |
| Ulceration | ||
| Ever | 17/50 | 34 |
| Folliculotropism | ||
| Ever | 35/47 | 74 |
| At LCT | 25/36 | 69 |
| Follicular mucin | 11/47 | 23 |
| At LCT | ||
| Eccrinotropism | ||
| Ever | 15/49 | 31 |
| At LCT | 8/40 | 20 |
| % large cells in skin at diagnosis of LCT | ||
| 100% | 15/42 | 36 |
| 25–75% | 27/42 | 64 |
| Fibrosis | ||
| Ever | 46/50 | 92 |
| At LCT | 33/41 | 80 |
| Vascular prominence | ||
| Ever | 48/50 | 96 |
| At LCT | 34/41 | 83 |
| Epidermal hyperplasia | ||
| Ever | 47/50 | 94 |
| Epidermotropism | ||
| Ever | 45/50 | 90 |
| At LCT | 34/40 | 85 |
| Pautrier microabscesses | ||
| Ever | 37/50 | 74 |
| At LCT | 27/41 | 66 |
| Neutrophils | ||
| Ever | 19/50 | 38 |
| At LCT | 10/41 | 24 |
DOD, dead of disease; Ever, at any time during follow-up period; LCT, large cell transformation; MF, mycosis fungoides.